Mystery Case Files: Huntsville is the first installment in the Mystery Case Files series of hidden object adventure games. In this game, players take on the role of a detective who is tasked to investigate and solve as series of crimes in the town of Huntsville located in Alabama. The player will discover that a criminal organization called S.T.A.I.N. is the group responsible for all the crimes in the area, and it is up the player to find clues and identify the villains behind the crimes. Each of the criminal group’s members has a Skeletal Head tattooed on a body part or leaves the mark behind on items.
Players are given a list of objects to find in a given scene that they must find. When all the objects have been found, players can progress to the next stage of the game or to another location. There are hints that can be used to help find objects. When players have completed their task of finding objects, they will be taken to the Crime Computer where they can solve timed puzzles to gather evidence to help in pinpointing criminals. This game has more than 15 crimes to solve spread out in more than 20 locations. The ultimate goal of the game is to capture S.T.A.I.N.’s big boss named Gertrude Goodlittle to end the crimes in Hunstville.