Call of Atlantis is a match three puzzle game. It is the third installment in the Atlantis series of games. Players must swap adjacent tiles on the grip to match three or more tiles of the same kind in a row or a column. There are different pieces of an artifact spread on the game grid. These artifacts must fall to the bottom of the grid in order to complete the level. There is also a game timer. The artifacts must be removed from the grid before the meter reaches the red area. There are also power-ups in the game, such as the Amulet of Poseidon. The amulet gets charged as the player makes matches of four. Once it is charged, it can be used to destroy a series of tiles on the grid. Another power-up is the Bomb of Titans, which appears randomly on the game screen. Users can collect the bomb by creating matches to bring the bomb at the bottom of the screen. The bomb allows the player to blast tiles on a chosen part of the game grid.
Apart from the match three game, Call of Atlantis also features a mini game in the form of a hidden object game. The player must find items that are hidden in a scene. The game features seven different locations – Greece, Babylon, Rome, Carthage, Troy, Poenicia, and Egypt.